It has an unusual round tower and a doorway decorated with flower motifs. The centre of Pienza was . completely re-designed in Renaissance times by Pope Pius II (seep47). Born here in 1405, when it was called Corsignano, Aeneas Sylvius Piccolomini became known as a leading Humanist scholar and philosopher. He was elected pope in 1458 and in the following year decided to Pienzaâ€™s piazza and Duomo, designed by Rossellino (1459) Courtyard in Palazzo Piccolomini The church of Madonna di San Biagio on the outskirts of Montepulciano Montepulciano Â© Road map E4. Ijjj 74,000. 0 Via Ricci 9. (0578) 75 86 87. H3 Thu.